Dengue-2 virus isolation from humans during an epizootic in southeastern Senegal in November, 1990.

Two days after returning from a week-long stay in southeastern Senegal, the first patient, a 31-year-old European, complained of a sudden influenza-like illness. Clinical data reported a sudden onset of fever (39"7C), shivers, frontal headache, myalgias, joint pains, nausea, vomiting and asthenia. No neurological syndrome, rash, haemorrhagic signs or hepatomegaly and splenomegaly were noticed. Thick smears were negative. Platelet counts (156 GigaA), white blood cells (4.9 Giga& and haemoglobin (17.6 g/dl) were normal. The patient, a resident of Senegal since May, 1989, had experienced several previous malaria attacks but no apparent arbovirosis. Clinical data from the second patient, a 15-year-old Senegalese living all-year round in the area, were not available. In both .